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NatMed 2025) and anti-apoptotic effects demonstrated in vivo in cardiac failure models and in vitro under stress conditions (Chapela, 2009

Clinical Efficacy at Each Dose In the SUSTAIN program, semaglutide 1.0 mg reduced HbA1c by 1.5% to 1.8% across trials, with weight loss ranging from 4.5 kg to 6.5 kg at 30 to 56 weeks [3]